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Cialis (Tadalafil) is used to treat erectile dysfunction (impotence - ED) and symptoms of benign prostatic hypertrophy (enlarged prostate). Another brand of sildenafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Tadalafil, known under the brand name Cialis for the treatment of erectile dysfunction and Adcirca for pulmonary arterial hypertension, is a PDE5 inhibitor. Its main competitors are sildenafil citrate (Viagra) and vardenafil (Levitra). Cialis was approved by the US FDA (Food and Drug Administration) on 21st November, 2003 for the treatment of erectile dysfunction. In May 2009 tadalafil was approved by the FDA for the treatment of pulmonary arterial hypertension.

Patients with erectile dysfunction take Cialis as needed. It should not be taken more frequently than once every 24 hours. For the medication to work, the man needs to be sexually aroused - it does not provide an instant erection without sexual stimulation. Cialis became nicknamed "the weekend pill" because its effects last 36 hours. Viagra and Levitra are effective for up to 8 hours. A PDE5 (phosphodiesterase type 5) inhibitor is a medication used to block the degradative action of cyclic GMP (cGMP) in the smooth muscle cells that line the blood vessels that supply the corpus cavernosa (two tubes that run the length of the penis). PDE5 is also present in the smooth muscle of the walls of the arteries within the lungs - hence, it has also been explored for pulmonary hypertension treatment.


What is erectile dysfunction?

Erectile dysfunction (ED), also known as impotence, is the inability to achieve or sustain an erection for satisfactory sexual activity. Erectile dysfunction is different from other conditions that interfere with male sexual intercourse, such as lack of sexual desire (decreased libido) and problems with ejaculation and orgasm (ejaculatory dysfunction). This article focuses on the evaluation and treatment of erectile dysfunction. Even though it may seem awkward to talk with your doctor about erectile dysfunction, go in for an evaluation. Problems getting or keeping an erection can be a sign of a health condition that needs treatment, such as heart disease or poorly controlled diabetes. Treating an underlying problem may be enough to reverse your erectile dysfunction.

About Erectile dysfunction

ED is primarily treated by tackling the cause of the problem, whether this is physical or psychological. The narrowing of the arteries (called atherosclerosis) is one of the most common causes of ED. In these cases your GP may suggest lifestyle changes, such as losing weight, to try to reduce your risk of cardiovascular disease. This may help to relieve your symptoms as well as improving your general health. You may also be given medication to treat atherosclerosis, such as cholesterol-lowering statins and drugs to reduce your blood pressure. There are several treatment options that have proved very successful for ED. Medication, such as Tadalafil (sold as Cialis), can be used to successfully manage it in at least two-thirds of men.